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AgONO‐Assisted Direct CH Arylation of Heteroarenes with Anilines
Author(s) -
Gowrisankar Saravanan,
Seayad Jayasree
Publication year - 2014
Publication title -
chemistry – a european journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.687
H-Index - 242
eISSN - 1521-3765
pISSN - 0947-6539
DOI - 10.1002/chem.201403640
Subject(s) - reagent , chemistry , nitrite , combinatorial chemistry , catalysis , copper , reaction conditions , organic chemistry , nitrate
A novel copper‐catalyzed CH arylation of heteroarenes with anilines by an in situ diazonium reaction is established by using silver nitrite (AgONO) as an unconventional nitrosating reagent under acid‐free conditions. It provides a complementary approach for the CH arylation of electron‐rich heteroarenes with aromatic amines affording a variety of heterobiaryls in moderate to good yields.