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Cyclodextrin Polyrotaxanes as a Highly Modular Platform for the Development of Imaging Agents
Author(s) -
Fredy Jean Wilfried,
Scelle Jérémy,
Guenet Aurélie,
Morel Elodie,
Adam de Beaumais Ségolène,
Ménand Mickaël,
Marvaud Valérie,
Bonnet Célia S.,
Tóth Eva,
Sollogoub Matthieu,
Vives Guillaume,
Hasenknopf Bernold
Publication year - 2014
Publication title -
chemistry – a european journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.687
H-Index - 242
eISSN - 1521-3765
pISSN - 0947-6539
DOI - 10.1002/chem.201403635
Subject(s) - modular design , bodipy , nanotechnology , cyclodextrin , fluorescence , supramolecular chemistry , supramolecular assembly , materials science , chemistry , computer science , molecule , organic chemistry , programming language , physics , quantum mechanics
Selectively functionalized cyclodextrins with a bodipy fluorescent tag or Gd 3+ complex were synthetized and threaded onto a polyammonium chain to form polyrotaxanes. This modular supramolecular assembly makes an ideal platform for bimodal (fluorescent and MRI) imaging applications.