Synthesis of Fluorinated Heteroaromatics through Formal Substitution of a Nitro Group by Fluorine under Transition‐Metal‐Free Conditions | Zendy

Guo RanNing | Zendy; Cai XianFeng | Zendy; Shi Lei | Zendy; Chen ZhangPei | Zendy; Zhou YongGui | Zendy

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Synthesis of Fluorinated Heteroaromatics through Formal Substitution of a Nitro Group by Fluorine under Transition‐Metal‐Free Conditions

Author(s) -

Guo RanNing,

Cai XianFeng,

Shi Lei,

Chen ZhangPei,

Zhou YongGui

Publication year - 2014

Publication title -

chemistry – a european journal

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.687

H-Index - 242

eISSN - 1521-3765

pISSN - 0947-6539

DOI - 10.1002/chem.201402282

Subject(s) - fluorine , nitro , transition metal , chemistry , electrophilic fluorination , electrophile , substitution (logic) , combinatorial chemistry , group (periodic table) , computational chemistry , organic chemistry , computer science , catalysis , alkyl , programming language

An efficient and transition‐metal‐free approach was developed to access a series of fluorinated heteroaromatics in moderate to excellent yields. This one‐pot procedure features a triple‐relay transformation of rapid dearomatization, fluorination, and rearomatization processes, which represents a conceptually novel strategy of combining partial hydrogenation and electrophilic fluorination.

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