Premium
A Two‐Armed Lanthanoid‐Chelating Paramagnetic NMR Probe Linked to Proteins via Thioether Linkages
Author(s) -
Liu WeiMin,
Skinner Simon P.,
Timmer Monika,
Blok Anneloes,
Hass Mathias A. S.,
Filippov Dmitri V.,
Overhand Mark,
Ubbink Marcellus
Publication year - 2014
Publication title -
chemistry – a european journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.687
H-Index - 242
eISSN - 1521-3765
pISSN - 0947-6539
DOI - 10.1002/chem.201400257
Subject(s) - thioether , lanthanide , paramagnetism , chelation , chemistry , crystallography , combinatorial chemistry , stereochemistry , inorganic chemistry , organic chemistry , ion , physics , quantum mechanics
Paramagnetic NMR probes provide valuable long‐range structural information on proteins and protein complexes. A new, stable, two‐armed lanthanoid probe is reported that can be attached to a protein site‐specifically via chemically inert thioether linkages.