Premium
Back Cover: The Toxicity of Graphene Oxides: Dependence on the Oxidative Methods Used (Chem. Eur. J. 25/2013)
Author(s) -
Chng Elaine Lay Khim,
Pumera Martin
Publication year - 2013
Publication title -
chemistry – a european journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.687
H-Index - 242
eISSN - 1521-3765
pISSN - 0947-6539
DOI - 10.1002/chem.201390092
Subject(s) - formazan , cytotoxicity , graphene , chemistry , bromide , oxidative phosphorylation , toxicity , salt (chemistry) , oxidative stress , nuclear chemistry , biochemistry , nanotechnology , materials science , inorganic chemistry , organic chemistry , in vitro
The cytotoxicity of graphene oxides (GOs) prepared by four oxidative treatments (Staudenmaier, Hofmann, Hummers, and Tour) was investigated by measuring the mitochondrial activity in adherent lung epithelial cells (A549) using the methylthiazolyldiphenyl‐tetrazolium bromide (MTT) assay and the water‐soluble tetrazolium salt (WST‐8) assay. A strong dose‐dependent cytotoxic response was shown after a 24 h exposure of the GO nanomaterials, suggesting that there is a correlation between the oxygen content and functional groups of GOs with their toxicological behavior. For more details, see the Full Paper by M. Pumera and E. L. K. Chng on pp. 8227 ff.