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Inside Cover: Fabrication of Layer‐by‐Layer Assembled Biomimetic Nanochannels for Highly Sensitive Acetylcholine Sensing (Chem. Eur. J. 24/2013)
Author(s) -
Wen Long,
Sun Zhongyue,
Han Cuiping,
Imene Boussouar,
Tian Demei,
Li Haibing,
Jiang Lei
Publication year - 2013
Publication title -
chemistry – a european journal
Language(s) - English
Resource type - Reports
SCImago Journal Rank - 1.687
H-Index - 242
eISSN - 1521-3765
pISSN - 0947-6539
DOI - 10.1002/chem.201390086
Subject(s) - acetylcholine , layer (electronics) , ionic bonding , nanotechnology , cover (algebra) , polymer , layer by layer , chemistry , fabrication , materials science , ion , organic chemistry , medicine , mechanical engineering , alternative medicine , pathology , engineering , endocrinology
Inspired by the role of acetylcholine in biological channels, biomimetic nanochannels were prepared in PET polymer films. The channel surface was modified with p ‐sulfonatocalix[4]arene (SCX4) by flexible layer‐by‐layer electrostatic assembly. The presence of acetylcholine (Ach) caused the occurrence of host–guest inclusion between SCX4 and Ach on the inner wall. Even at low concentrations of Ach (1 n M ), there was an obvious change in the rectified ionic flux. For more details, see the Communication by H. Li et al. on page 7686 ff.