Palladium(II)‐Catalyzed ortho ‐CH Arylation/Alkylation of N ‐Benzoyl α‐Amino Ester Derivatives

The palladium‐catalyzed arylation/alkylation of ortho ‐CH bonds in N ‐benzoyl α‐amino ester derivatives is described. In such a system both the NH‐amido and the CO 2 R groups in the α‐amino ester moieties play a role in successful CH activation/CC bond formation using iodoaryl coupling partners. A wide variety of functional groups and electron‐rich/deficient iodoarenes are tolerated. The yields obtained range from 20 to 95 %.