Potassium  N ‐Iodo  p ‐Toluenesulfonamide (TsNIK, Iodamine‐T): A New Reagent for the Oxidation of Hydrazones to Diazo Compounds | Zendy

Nicolle Simon M. | Zendy; Moody Christopher J. | Zendy

Premium

Potassium N ‐Iodo p ‐Toluenesulfonamide (TsNIK, Iodamine‐T): A New Reagent for the Oxidation of Hydrazones to Diazo Compounds

Author(s) -

Nicolle Simon M.,

Moody Christopher J.

Publication year - 2014

Publication title -

chemistry – a european journal

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.687

H-Index - 242

eISSN - 1521-3765

pISSN - 0947-6539

DOI - 10.1002/chem.201304656

Subject(s) - diazo , reagent , hydrazone , chemistry , yield (engineering) , potassium , organic chemistry , medicinal chemistry , metallurgy , materials science

A new reagent for the oxidation of hydrazones to diazo compounds is described. N ‐Iodo p ‐toluenesulfonamide (TsNIK, iodamine‐T) allows the preparation of α‐diazoesters, α‐diazoamides, α‐diazoketones and α‐diazophosphonates in good yield and in high purity after a simple extractive work‐up. α‐Diazoesters were also obtained in high yield from the corresponding ketones through a one‐pot process of hydrazone formation/oxidation.

This content is not available in your region!

Continue researching here.

Having issues? You can contact us here

Accelerating Research