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Cooperative Effect of Two Metals: CoPd(OAc) 4 ‐Catalyzed CH Amination and Aziridination
Author(s) -
Huang GuanHao,
Li JianMin,
Huang JingJyun,
Lin JyunDai,
Chuang Gary Jing
Publication year - 2014
Publication title -
chemistry – a european journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.687
H-Index - 242
eISSN - 1521-3765
pISSN - 0947-6539
DOI - 10.1002/chem.201304633
Subject(s) - amination , intramolecular force , catalysis , chemistry , medicinal chemistry , combinatorial chemistry , organic chemistry
The first Co/Pd‐cocatalyzed intramolecular CH amination and aziridination reactions were developed. Sulfamate esters were converted to oxathiazinanes by using CoPd(OAc) 4 as catalyst and PhI(OAc) 2 as oxidant. The mutual presence of both Co and Pd is crucial for the catalytic activity. This combination of two metals with simple acetate ligands provides an economical alternative to the Rh‐catalyzed insertion of nitrenoids into CH bonds.