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Cyclization‐Induced Turn‐On Fluorescence System Applicable to Dicarboxylate Sensing
Author(s) -
Noguchi Takao,
Roy Bappaditya,
Yoshihara Daisuke,
Tsuchiya Youichi,
Yamamoto Tatsuhiro,
Shinkai Seiji
Publication year - 2014
Publication title -
chemistry – a european journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.687
H-Index - 242
eISSN - 1521-3765
pISSN - 0947-6539
DOI - 10.1002/chem.201304031
Subject(s) - turn (biochemistry) , fluorescence , chemistry , combinatorial chemistry , biophysics , biochemistry , biology , physics , quantum mechanics
A novel tetraphenylethene‐based fluorescence (FL) chemosensor exhibits nonlinear turn‐on FL switching though cooperative binding of L ‐tartarate, where its convergent binding to form cyclic substructures is responsible for the FL increase. This binding scheme achieves selective detection of dicarboxylates over monocarboxylates, thus is potentially applicable to the preliminary screening for metabolic disorders.