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An Unusual Triphenylphosphine Oxide Catalyzed Stereoselective 1,3‐Dichlorination of Unsaturated Ketoesters
Author(s) -
Yu TianYang,
Wang Yao,
Xu PengFei
Publication year - 2014
Publication title -
chemistry – a european journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.687
H-Index - 242
eISSN - 1521-3765
pISSN - 0947-6539
DOI - 10.1002/chem.201303688
Subject(s) - stereoselectivity , triphenylphosphine oxide , triphenylphosphine , catalysis , chemistry , cascade , complementation , combinatorial chemistry , oxide , organic chemistry , gene , biochemistry , chromatography , phenotype
An unusual Ph 3 PO‐catalyzed stereoselective 1,3‐dicholorination of an unsaturated ketoester has been developed. The novel activation mode involved in this cascade reaction can promote consecutively elusive transformations. The products were obtained with good yields and excellent stereoselectivities. This reaction makes important complementation to the limitations associated with the field of dichlorination.