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Water Compatible Multicomponent Cascade Suzuki/Heck–Aldol, Suzuki–Aldol–Suzuki, and Aldol–Suzuki–Aldol Reactions: An Ecofriendly Paradigm for Multiple CarbonCarbon Bond Formation in One Pot
Author(s) -
Kumar Rajesh,
Andhare Nitin H.,
Shard Amit,
Sinha Arun K.
Publication year - 2013
Publication title -
chemistry – a european journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.687
H-Index - 242
eISSN - 1521-3765
pISSN - 0947-6539
DOI - 10.1002/chem.201303069
Subject(s) - aldol reaction , chemistry , reagent , organic chemistry , suzuki reaction , substrate (aquarium) , ligand (biochemistry) , combinatorial chemistry , palladium , catalysis , biology , biochemistry , ecology , receptor
Aryls in hot water : A versatile strategy has been devised for the synthesis of biologically active biaryl(hetero)chalcones from readily available precursors (see scheme). The method is step, pot, and carbon economic, ligand‐free, devoid of toxic reagents/solvents, and has a wide substrate scope.
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