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α‐Isocupreine, an Enantiocomplementary Catalyst of β‐Isocupreidine
Author(s) -
Nakamoto Yoshito,
Urabe Fumiya,
Takahashi Keisuke,
Ishihara Jun,
Hatakeyama Susumi
Publication year - 2013
Publication title -
chemistry – a european journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.687
H-Index - 242
eISSN - 1521-3765
pISSN - 0947-6539
DOI - 10.1002/chem.201302665
Subject(s) - catalysis , combinatorial chemistry , chemistry , scheme (mathematics) , quinine , organic chemistry , computer science , mathematics , medicine , mathematical analysis , malaria , immunology
Complementary chemistry! α‐Isocupreine (α‐ICPN) was synthesized for the first time in one step from quinine by treatment with CF 3 SO 3 H (see scheme). This compound serves as an enantiocomplementary catalyst to β‐isocupreidine (β‐ICD) in the Morita–Baylis–Hillman reaction.