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A Novel Double Carbonylation Reaction of Aryl Halides: Selective Synthesis of 5‐Arylfuranones
Author(s) -
Schranck Johannes,
Wu XiaoFeng,
Tlili Anis,
Neumann Helfried,
Beller Matthias
Publication year - 2013
Publication title -
chemistry – a european journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.687
H-Index - 242
eISSN - 1521-3765
pISSN - 0947-6539
DOI - 10.1002/chem.201302092
Subject(s) - regioselectivity , novelty , aryl , carbonylation , halide , computer science , combinatorial chemistry , yield (engineering) , chemistry , organic chemistry , materials science , catalysis , alkyl , psychology , carbon monoxide , metallurgy , social psychology
Double CO inCOrporation : An atom‐efficient synthesis of 4‐arylfuranones from aryl halides, two molecules of CO, and terminal alkenes is reported (see scheme). 18 different 4‐arylfuranones were synthesized in up to 83 % yield in a straightforward manner and with high regioselectivity. The range of the new 4‐arylfuranones synthesized demonstrates the value and novelty of this procedure.