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Copper‐Catalyzed Direct Synthesis of Iodoenamides from Ketoximes
Author(s) -
Liang Hao,
Ren ZhiHui,
Wang YaoYu,
Guan ZhengHui
Publication year - 2013
Publication title -
chemistry – a european journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.687
H-Index - 242
eISSN - 1521-3765
pISSN - 0947-6539
DOI - 10.1002/chem.201301785
Subject(s) - copper , chemistry , catalysis , iodide , dichloroethane , combinatorial chemistry , electron transfer , 1,2 dichloroethane , organic chemistry
Iodide in copper's pathway : A new, efficient, and practical copper‐catalyzed synthesis of Z ‐iodoenamides from readily available ketoximes has been developed (see scheme). The reaction was believed to proceed through a single‐electron‐transfer pathway. The corresponding Z ‐iodoenamides have been applied to the synthesis of substituted oxazoles, dienes, β‐phenoxyl enamides, eneynes, β‐acylenamides, and pyrroles (DCE=1,2‐dichloroethane).
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