Premium
Gold Carbenes from Substituted Propargyl Acetates: Intramolecular Ene‐type Reactions to 2‐Acetoxynaphthalene Derivatives
Author(s) -
Oh Chang Ho,
Kim Ji Hee,
Piao Lanhua,
Yu Jin,
Kim So Young
Publication year - 2013
Publication title -
chemistry – a european journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.687
H-Index - 242
eISSN - 1521-3765
pISSN - 0947-6539
DOI - 10.1002/chem.201301384
Subject(s) - propargyl , ene reaction , intramolecular force , chemistry , catalysis , product (mathematics) , type (biology) , combinatorial chemistry , computer science , medicinal chemistry , organic chemistry , mathematics , ecology , geometry , biology
A new Au‐catalyzed cascade reaction was developed for the conversion of propargylic acetates 1 to benzannulated products 2 in good to excellent yields. The gold catalyst is involved in generating intermediate A and in the ene‐type reaction of intermediate B for the formation of product 2 (see scheme).