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Total Synthesis of Jadomycins B, S, T, and ILEVS1080
Author(s) -
Yang Xiaoyu,
Yu Biao
Publication year - 2013
Publication title -
chemistry – a european journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.687
H-Index - 242
eISSN - 1521-3765
pISSN - 0947-6539
DOI - 10.1002/chem.201301297
Subject(s) - condensation , total synthesis , chemistry , computer science , stereochemistry , physics , thermodynamics
Sweetening up jadomycin A : The first total synthesis of jadomycins B, S, T, and ILEVS1080 has been achieved, featuring construction of the unique 8 H ‐benz[ b ]oxazolo[3,3‐f]phenanthridine skeleton by biomimetic condensation of a quinone aldehyde with amino acid sodium salts and elaboration of the glycosides by Mitsunobu condensation (see figure).