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Synthesis of C8N9 Annulated Purines by Iron‐Catalyzed CH Amination
Author(s) -
Maes Jens,
Rauws Tom R. M.,
Maes Bert U. W.
Publication year - 2013
Publication title -
chemistry – a european journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.687
H-Index - 242
eISSN - 1521-3765
pISSN - 0947-6539
DOI - 10.1002/chem.201301248
Subject(s) - amination , catalysis , purine , chemistry , combinatorial chemistry , computer science , organic chemistry , enzyme
Purine and simple : A short synthesis for substituted annulated purine derivatives based on an Fe‐catalyzed direct amination reaction using oxygen as oxidant was developed (see scheme). Interestingly, iron proved to be superior to copper catalysis.
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