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Ruthenium‐Containing Phosphinesulfonate Chelate for the Hydrogenation of Aryl Ketones
Author(s) -
Jiang Fan,
Yuan Kedong,
Achard Mathieu,
Bruneau Christian
Publication year - 2013
Publication title -
chemistry – a european journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.687
H-Index - 242
eISSN - 1521-3765
pISSN - 0947-6539
DOI - 10.1002/chem.201301201
Subject(s) - ruthenium , aryl , chelation , chemistry , amine gas treating , noyori asymmetric hydrogenation , catalysis , ligand (biochemistry) , base (topology) , medicinal chemistry , asymmetric hydrogenation , organic chemistry , polymer chemistry , combinatorial chemistry , enantioselective synthesis , mathematical analysis , biochemistry , alkyl , receptor , mathematics
Various ruthenium(II) complexes that contain phosphinesulfonate chelate have been synthesized. Arene‐free complexes were found to be efficient in the base‐free hydrogenation of various aryl ketones, whereas the arene‐containing precatalysts required the presence of an amine as an additive. The seminal asymmetric hydrogenation reaction by using the new Sulfo‐Binepine ligand was also investigated for the possible intervention of a dihydride species.