Premium
Total Synthesis of Starfish Saponin Goniopectenoside B
Author(s) -
Xiao Guozhi,
Yu Biao
Publication year - 2013
Publication title -
chemistry – a european journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.687
H-Index - 242
eISSN - 1521-3765
pISSN - 0947-6539
DOI - 10.1002/chem.201301186
Subject(s) - starfish , saponin , yield (engineering) , chemistry , biology , ecology , physics , medicine , alternative medicine , pathology , thermodynamics
Star quality : Goniopectenoside B, a minor asterosaponin from starfish Goniopecten demonstrans with antifouling activity, has been synthesized in a convergent 21 steps and in 4.3 % overall yield starting from adrenosterone. This represents the first synthesis of a complex asterosaponin, which are ubiquitous and characteristic in starfish as defense chemicals (see figure).