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Rh‐Catalyzed Highly Enantioselective Hydrogenation of Nitroalkenes under Basic Conditions
Author(s) -
Li Shengkun,
Huang Kexuan,
Zhang Jiwen,
Wu Wenjun,
Zhang Xumu
Publication year - 2013
Publication title -
chemistry – a european journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.687
H-Index - 242
eISSN - 1521-3765
pISSN - 0947-6539
DOI - 10.1002/chem.201301049
Subject(s) - enantioselective synthesis , catalysis , chemistry , organic chemistry , combinatorial chemistry , asymmetric hydrogenation
Go catalytic! A highly enantioselective hydrogenation of β,β‐disubstituted nitroalkenes and isomeric mixtures of nitroalkenes by using a Rh/DuanPhos catalytic system under basic conditions has furnished a convenient approach to β‐chiral nitroalkanes, which are otherwise not so easy to make (see scheme).