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Phosphate‐Tether‐Mediated Ring‐Closing Metathesis for the Preparation of Complex 1,3‐ anti ‐Diol‐Containing Subunits
Author(s) -
Chegondi Rambabu,
Maitra Soma,
Markley Jana L.,
Hanson Paul R.
Publication year - 2013
Publication title -
chemistry – a european journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.687
H-Index - 242
eISSN - 1521-3765
pISSN - 0947-6539
DOI - 10.1002/chem.201300913
Subject(s) - ring closing metathesis , phosphate , metathesis , chemistry , stereochemistry , salt metathesis reaction , alcohol , combinatorial chemistry , organic chemistry , polymerization , polymer
An array of examples of diastereoselective, phosphate‐tether‐mediated ring‐closing metathesis reactions, which highlight the importance of product ring size and substrate stereochemical compatibility, as well as complexity, is reported. Studies focus primarily on the formation of bicyclo[ n .3.1]phosphates, involving the coupling of C 2 ‐symmetric dienediol subunits with a variety of simple, as well as complex, alcohol partners.