Premium
Microwave‐Accelerated Ru‐Catalyzed Hydrovinylation of Alkynes and Enynes: A Straightforward Approach toward 1,3‐Dienes and 1,3,5‐Trienes
Author(s) -
Schabel Tobias,
Plietker Bernd
Publication year - 2013
Publication title -
chemistry – a european journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.687
H-Index - 242
eISSN - 1521-3765
pISSN - 0947-6539
DOI - 10.1002/chem.201300790
Subject(s) - catalysis , service (business) , computer science , protocol (science) , combinatorial chemistry , acrylate , range (aeronautics) , chemistry , microwave , world wide web , organic chemistry , business , telecommunications , materials science , medicine , alternative medicine , monomer , pathology , marketing , polymer , composite material
Quick, but not dirty! Microwave heating was found to have a significant effect on the Ru‐catalyzed hydrovinylations of alkynes. A broad range of different terminal alkynes were coupled to methyl acrylate within just 30 min in good to excellent yields (see scheme). This new protocol was transferred to the hydrovinylation of enynes as novel coupling partners in CH‐activation chemistry giving different 1,3,5‐trienes as the sole products.