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Transition‐Metal‐Free One‐Pot Synthesis of Biaryls from Grignard Reagents and Substituted Cyclohexanones
Author(s) -
Zhou Feng,
Simon MarcOliver,
Li ChaoJun
Publication year - 2013
Publication title -
chemistry – a european journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.687
H-Index - 242
eISSN - 1521-3765
pISSN - 0947-6539
DOI - 10.1002/chem.201300491
Subject(s) - aromatization , grignard reagent , transition metal , chemistry , grignard reaction , reagent , dehydration , combinatorial chemistry , organic chemistry , catalysis , biochemistry
A new strategy for the construction of biaryls by a transition‐metal‐free process is presented. A sequence of a Grignard reaction, dehydration, and oxidative aromatization affords the desired products in a one‐pot fashion.