Premium
A Concise Synthesis of L ‐Pyrrolysine
Author(s) -
Han ManYi,
Wang HuaiZhen,
An WanKai,
Jia JuYing,
Ma BaoChun,
Zhang Yuan,
Wang Wei
Publication year - 2013
Publication title -
chemistry – a european journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.687
H-Index - 242
eISSN - 1521-3765
pISSN - 0947-6539
DOI - 10.1002/chem.201300403
Subject(s) - computer science , simple (philosophy) , combinatorial chemistry , chemistry , epistemology , philosophy
Organocatalysis : A concise synthesis of L ‐pyrrolysine has been accomplished in six steps from simple starting materials. The facile synthetic strategy relies on an organocatalytic Michael addition, an efficient amide coupling, and a challenging method for the imine‐bond construction (see scheme).