Premium
A Concise Synthesis of L ‐Pyrrolysine
Author(s) -
Han ManYi,
Wang HuaiZhen,
An WanKai,
Jia JuYing,
Ma BaoChun,
Zhang Yuan,
Wang Wei
Publication year - 2013
Publication title -
chemistry – a european journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.687
H-Index - 242
eISSN - 1521-3765
pISSN - 0947-6539
DOI - 10.1002/chem.201300403
Subject(s) - computer science , simple (philosophy) , combinatorial chemistry , chemistry , epistemology , philosophy
Organocatalysis : A concise synthesis of L ‐pyrrolysine has been accomplished in six steps from simple starting materials. The facile synthetic strategy relies on an organocatalytic Michael addition, an efficient amide coupling, and a challenging method for the imine‐bond construction (see scheme).
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom