Selective, Sensitive, and Rapid Analysis with Lateral‐Flow Assays Based on Antibody‐Gated Dye‐Delivery Systems: The Example of Triacetone Triperoxide | Zendy

Climent Estela | Zendy; Gröninger Delia | Zendy; Hecht Mandy | Zendy; Walter M. Astrid | Zendy; MartínezMáñez Ramón | Zendy; Weller Michael G. | Zendy; Sancenón Félix | Zendy; Amorós Pedro | Zendy; Rurack Knut | Zendy

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Selective, Sensitive, and Rapid Analysis with Lateral‐Flow Assays Based on Antibody‐Gated Dye‐Delivery Systems: The Example of Triacetone Triperoxide

Author(s) -

Climent Estela,

Gröninger Delia,

Hecht Mandy,

Walter M. Astrid,

MartínezMáñez Ramón,

Weller Michael G.,

Sancenón Félix,

Amorós Pedro,

Rurack Knut

Publication year - 2013

Publication title -

chemistry – a european journal

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.687

H-Index - 242

eISSN - 1521-3765

pISSN - 0947-6539

DOI - 10.1002/chem.201300031

Subject(s) - analyte , chemistry , fluorescence , chromatography , combinatorial chemistry , analytical chemistry (journal) , quantum mechanics , physics

Set them free : Brightly fluorescent indicators that are loaded into mesoporous silica nanoparticle carriers, capped with bulky antibodies, are released into the lateral flow of a test strip upon analyte arrival. Integration of the system into a rapid, simple flow test with fluorescence readout is applied for the selective and sensitive determination of the presence of triacetone triperoxide (TATP) as a prototype small‐molecule analyte (see figure).

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