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Cover Picture: Highly Enantioselective Epoxidation of Multisubstituted Enones Catalyzed by Non‐Heme Iron Catalysts (Chem. Eur. J. 24/2012)
Author(s) -
Wang Bin,
Wang Shoufeng,
Xia Chungu,
Sun Wei
Publication year - 2012
Publication title -
chemistry – a european journal
Language(s) - English
Resource type - Reports
SCImago Journal Rank - 1.687
H-Index - 242
eISSN - 1521-3765
pISSN - 0947-6539
DOI - 10.1002/chem.201290097
Subject(s) - chemistry , catalysis , molecule , enantioselective synthesis , dioxygenase , stereochemistry , quartz crystal microbalance , crystallography , combinatorial chemistry , photochemistry , organic chemistry , adsorption , enzyme
The non‐heme iron(II) complexes of N 4 ligands, derived from proline and benzimidazole, exhibited an unprecedented activity and enantioselectivity for the epoxidation of a variety of di‐ and trisubstituted enones. X‐ray analysis of the iron complex revealed that the ligand coordinated the iron center in a cis ‐α topology. The 18 O‐isotopic‐labeling experiments suggest that high‐valent FeO species are involved as the active oxidant in the catalytic process. For more details, see the Communication by W. Sun et al. on page 7332 ff.