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Development of Metal/Organo Catalytic Systems for Direct Vinylogous Michael Reactions to Build Chiral γ,γ‐Disubstituted Butenolides
Author(s) -
Yang Dongxu,
Wang Linqing,
Zhao Depeng,
Han Fengxia,
Zhang Bangzhi,
Wang Rui
Publication year - 2013
Publication title -
chemistry – a european journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.687
H-Index - 242
eISSN - 1521-3765
pISSN - 0947-6539
DOI - 10.1002/chem.201204466
Subject(s) - dual (grammatical number) , conjugate , catalysis , computer science , aryl , metal , chemistry , combinatorial chemistry , alkyl , organic chemistry , philosophy , mathematics , mathematical analysis , linguistics
Vinylogous reactions : The direct asymmetric vinylogous conjugate additions of γ‐aryl‐ and alkyl‐substituted butenolides to enones was realized for the first time by a designed and tested metal/organo dual‐activation strategy, in which two effective metal/organo cooperative catalytic systems have been built (see scheme).