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Direct Electrosynthesis of Ketones from Benzylic Methylenes by Electrooxidative CH Activation
Author(s) -
Meng Li,
Su Jihu,
Zha Zhenggen,
Zhang Li,
Zhang Zhenlei,
Wang Zhiyong
Publication year - 2013
Publication title -
chemistry – a european journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.687
H-Index - 242
eISSN - 1521-3765
pISSN - 0947-6539
DOI - 10.1002/chem.201204207
Subject(s) - electrosynthesis , chemistry , reaction mechanism , combinatorial chemistry , catalysis , electrochemistry , organic chemistry , electrode
Electrify your chemistry! Direct electrosynthesis of ketones from benzylic methylenes in an undivided cell was realized in moderate to good yields (see scheme). In this electrosynthesis, electrons instead of conventional oxidants and catalysts are employed to make the reaction environmentally benign. Moreover, the reaction intermediate radical was detected by ESR spectroscopy and the reaction mechanism was clarified.