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Label‐Free Colorimetric Detection of Arsenite Utilizing G‐/T‐Rich Oligonucleotides and Unmodified Au Nanoparticles
Author(s) -
Liang RuPing,
Wang ZhongXia,
Zhang Li,
Qiu JianDing
Publication year - 2013
Publication title -
chemistry – a european journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.687
H-Index - 242
eISSN - 1521-3765
pISSN - 0947-6539
DOI - 10.1002/chem.201203402
Subject(s) - arsenite , oligonucleotide , nanoparticle , chemistry , chromatography , combinatorial chemistry , nanotechnology , materials science , arsenic , organic chemistry , biochemistry , dna
“Free” arsenite sensor : Based on the principle that G‐/T‐rich single‐stranded DNA (ssDNA) and folded DNA bound to arsenite have different propensities to adsorb onto Au nanoparticles (Au NPs) in colloidal solution, a label‐free colorimetric assay for arsenite sensing based on color changes associated with the aggregation of Au NPs has been designed (see scheme).