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Highly Enantioselective Imine Hydrogenation Catalyzed by Ruthenium Phosphane–Phosphite Diamine Complexes
Author(s) -
Vaquero Mónica,
Suárez Andrés,
Vargas Sergio,
Bottari Giovanni,
Álvarez Eleuterio,
Pizzano Antonio
Publication year - 2012
Publication title -
chemistry – a european journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.687
H-Index - 242
eISSN - 1521-3765
pISSN - 0947-6539
DOI - 10.1002/chem.201203193
Subject(s) - enantioselective synthesis , imine , ruthenium , diamine , catalysis , ligand (biochemistry) , chemistry , combinatorial chemistry , aryl , organic chemistry , noyori asymmetric hydrogenation , biochemistry , alkyl , receptor
Mildly does it : A highly enantioselective catalyst for the hydrogenation of N ‐aryl imines is described (see scheme). This catalyst offers practical advantages because it operates under very mild conditions and is based on an Ru complex with a diamine as the sole chiral ligand.