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Copper‐ and Phosphine‐Ligand‐Free Palladium‐Catalyzed Direct Allylation of Electron‐Deficient Polyfluoroarenes with Allylic Chlorides
Author(s) -
Yu YanBo,
Fan Shilu,
Zhang Xingang
Publication year - 2012
Publication title -
chemistry – a european journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.687
H-Index - 242
eISSN - 1521-3765
pISSN - 0947-6539
DOI - 10.1002/chem.201202824
Subject(s) - phosphine , allylic rearrangement , palladium , chemistry , catalysis , ligand (biochemistry) , copper , combinatorial chemistry , organic chemistry , biochemistry , receptor
Simply id(all)ylic : A copper‐ and phosphine‐ligand‐free Pd‐catalyzed direct allylation of electron‐deficient polyfluoroarenes with allylic chlorides and the reaction mechanism are described (see scheme). The simple catalytic system, broad substrate scope, and excellent functional‐group compatibility of this protocol provides a useful and facile access to allylated polyfluoroarenes.