Premium
A General and Efficient Palladium‐Catalyzed Carbonylative Synthesis of 2‐Aryloxazolines and 2‐Aryloxazines from Aryl Bromides
Author(s) -
Wu XiaoFeng,
Neumann Helfried,
Neumann Stephan,
Beller Matthias
Publication year - 2012
Publication title -
chemistry – a european journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.687
H-Index - 242
eISSN - 1521-3765
pISSN - 0947-6539
DOI - 10.1002/chem.201202652
Subject(s) - oxazoline , ring (chemistry) , palladium , aryl , catalysis , chemistry , combinatorial chemistry , medicinal chemistry , organic chemistry , alkyl
Oxazoline is OK! A general and efficient method for the synthesis of oxazolines has been developed (see scheme). This allowed the preparation of 27 five‐membered‐ring heterocycles and 11 six‐membered‐ring heterocycles in moderate to good yields.