Cobalt(II)‐Catalyzed 1,4‐Addition of Organoboronic Acids to Activated Alkenes: An Application to Highly  cis ‐Stereoselective Synthesis of Aminoindane Carboxylic Acid Derivatives | Zendy

Chen MinHsien | Zendy; Mannathan Subramaniyan | Zendy; Lin PaoShun | Zendy; Cheng ChienHong | Zendy

Premium

Cobalt(II)‐Catalyzed 1,4‐Addition of Organoboronic Acids to Activated Alkenes: An Application to Highly cis ‐Stereoselective Synthesis of Aminoindane Carboxylic Acid Derivatives

Author(s) -

Chen MinHsien,

Mannathan Subramaniyan,

Lin PaoShun,

Cheng ChienHong

Publication year - 2012

Publication title -

chemistry – a european journal

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.687

H-Index - 242

eISSN - 1521-3765

pISSN - 0947-6539

DOI - 10.1002/chem.201202575

Subject(s) - stereoselectivity , chemistry , catalysis , cobalt , annulation , organic chemistry , carboxylic acid , medicinal chemistry

It all adds up : The 1,4‐addition of organoboronic acids to activated alkenes catalyzed by [Co(dppe)Cl 2 ] is described. A [3+2]‐annulation reaction of ortho ‐iminoarylboronic acids with acrylates to give various aminoindane carboxylic acid derivatives with cis ‐stereoselectivity is also demonstrated (see scheme; dppe=1,2‐bis(diphenylphosphino)ethane).

This content is not available in your region!

Continue researching here.

Having issues? You can contact us here

Accelerating Research