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Iron‐Catalyzed CH Hydroxylation and Olefin cis ‐Dihydroxylation Using a Single‐Electron Oxidant and Water as the Oxygen‐Atom Source
Author(s) -
GarciaBosch Isaac,
Codolà Zoel,
Prat Irene,
Ribas Xavi,
LloretFillol Julio,
Costas Miquel
Publication year - 2012
Publication title -
chemistry – a european journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.687
H-Index - 242
eISSN - 1521-3765
pISSN - 0947-6539
DOI - 10.1002/chem.201202147
Subject(s) - dihydroxylation , hydroxylation , cerium , catalysis , chemistry , oxygen atom , olefin fiber , medicinal chemistry , organic chemistry , molecule , enantioselective synthesis , enzyme
Bioinspired oxidation : The hydroxylation of alkanes with retention of the configuration and the cis ‐dihydroxylation of olefins can be accomplished using [Fe II (CF 3 SO 3 ) 2 ( Me,H PyTACN)] ( 1 ) as a catalyst, water as an oxygen‐atom source, and cerium ammonium nitrate (CAN) as a single‐electron oxidant. The oxidation of CH bonds and CC bonds, as well as water oxidation involves a common reaction intermediate formed by the reaction of CAN and [Fe IV (O)(OH 2 )( Me,H PyTACN)] + .