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Visual Detection of Glucose Using Conformational Switch of i‐Motif DNA and Non‐Crosslinking Gold Nanoparticles
Author(s) -
Li Wen,
Feng Lingyan,
Ren Jinsong,
Wu Li,
Qu Xiaogang
Publication year - 2012
Publication title -
chemistry – a european journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.687
H-Index - 242
eISSN - 1521-3765
pISSN - 0947-6539
DOI - 10.1002/chem.201201914
Subject(s) - motif (music) , colloidal gold , dna , nanoparticle , chemistry , structural motif , nanotechnology , biophysics , combinatorial chemistry , biochemistry , materials science , biology , art , aesthetics
i‐Motif tuned : Glucose is a ubiquitous fuel for metabolic pathways; its oxidation can trigger i‐motif DNA formation. Using this unique conformational switch and non‐crosslinking gold nanoparticles, a label‐free colorimetric glucose sensor has been developed (see illustration).