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Direct α‐Functionalization of Saturated Cyclic Amines
Author(s) -
Mitchell Emily A.,
Peschiulli Aldo,
Lefevre Nicolas,
Meerpoel Lieven,
Maes Bert U. W.
Publication year - 2012
Publication title -
chemistry – a european journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.687
H-Index - 242
eISSN - 1521-3765
pISSN - 0947-6539
DOI - 10.1002/chem.201201539
Subject(s) - surface modification , cyclic amines , chemistry , reactive intermediate , transition metal , combinatorial chemistry , polymer chemistry , catalysis , organic chemistry
Recent advances in synthetic methods for the direct α‐functionalization of saturated cyclic amines are described. Methods are categorized according to the in situ formed reactive intermediate (α‐amino cation, α‐amino anion, and α‐amino radical). Transition‐metal‐catalyzed reactions involving other intermediates have been treated as a separate and fourth class.