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Rhodium‐Catalyzed Linear Cross‐Trimerization of Two Different Alkynes with an Alkene and Two Different Alkenes with an Alkyne
Author(s) -
Kobayashi Masayuki,
Tanaka Ken
Publication year - 2012
Publication title -
chemistry – a european journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.687
H-Index - 242
eISSN - 1521-3765
pISSN - 0947-6539
DOI - 10.1002/chem.201200903
Subject(s) - binap , alkyne , rhodium , cationic polymerization , alkene , chemistry , medicinal chemistry , catalysis , polymer chemistry , organic chemistry , enantioselective synthesis
Crossing paths with rhodium : A cationic Rh I /H 8 ‐BINAP complex has been found to catalyze the linear cross‐trimerization of terminal alkynes, acetylenedicarboxylates, and acrylamides to give substituted trienes. The asymmetric linear cross‐trimerization, giving substituted chiral dienes, has also been achieved by using monosubstituted alkenes and ( R )‐BINAP instead of terminal alkynes and H 8 ‐BINAP (see scheme; H 8 ‐BINAP=2,2′‐bis(diphenylphosphino)‐5,5′,6,6′,7,7′,8,8′‐octahydro‐1,1′‐binaphthyl; BINAP=2,2′‐bis(diphenylphosphino)‐1,1′‐binaphthyl]).