Copper‐Catalyzed Formation of CO Bonds by Direct α‐CH Bond Activation of Ethers Using Stoichiometric Amounts of Peroxide in Batch and Continuous‐Flow Formats | Zendy

Kumar G. Sathish | Zendy; Pieber Bartholomäus | Zendy; Reddy K. Rajender | Zendy; Kappe C. Oliver | Zendy

Premium

Copper‐Catalyzed Formation of CO Bonds by Direct α‐CH Bond Activation of Ethers Using Stoichiometric Amounts of Peroxide in Batch and Continuous‐Flow Formats

Author(s) -

Kumar G. Sathish,

Pieber Bartholomäus,

Reddy K. Rajender,

Kappe C. Oliver

Publication year - 2012

Publication title -

chemistry – a european journal

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.687

H-Index - 242

eISSN - 1521-3765

pISSN - 0947-6539

DOI - 10.1002/chem.201200815

Subject(s) - peroxide , chemistry , catalysis , microreactor , acetal , stoichiometry , organic peroxide , copper , phenols , organic chemistry , polymer chemistry , combinatorial chemistry , copolymer , polymer

Peroxides and ethers in flow : 2‐Carbonyl‐substituted phenols and β‐ketoesters react safely with ethers in a microreactor environment using a copper catalyst and an organic peroxide (TBHP). This protocol results in unsymmetrical acetal scaffolds not easily available otherwise (see scheme).

This content is not available in your region!

Continue researching here.

Having issues? You can contact us here

Accelerating Research