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Enantioselective Hydrosilylation with Chiral Frustrated Lewis Pairs
Author(s) -
Chen Dianjun,
Leich Valeri,
Pan Fangfang,
Klankermayer Jürgen
Publication year - 2012
Publication title -
chemistry – a european journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.687
H-Index - 242
eISSN - 1521-3765
pISSN - 0947-6539
DOI - 10.1002/chem.201200244
Subject(s) - enantioselective synthesis , hydrosilylation , frustrated lewis pair , catalysis , computer science , chemistry , organic chemistry , lewis acids and bases
Frustrated partners : Based on an initial mechanistic investigation, enantioselective hydrosilylation of various imines was accomplished for the first time by using a novel chiral frustrated Lewis pair (FLP) catalyst. High enantioselectivities of up to 87 % were obtained demonstrating the effectiveness of these metal‐free chiral catalysts for this transformation (see scheme).