Platinum‐Catalyzed Cyclization/[1,2]‐Alkyl Migration/Allyl Shift/Cyclization Cascade of Epoxy Alkynyl Allyl Ethers: A Step‐Economical Route to Spirobenzo[ h ]chromanones | Zendy

Yang YanFang | Zendy; Shu XingZhong | Zendy; Luo JianYi | Zendy; Ali Shaukat | Zendy; Liang YongMin | Zendy

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Platinum‐Catalyzed Cyclization/[1,2]‐Alkyl Migration/Allyl Shift/Cyclization Cascade of Epoxy Alkynyl Allyl Ethers: A Step‐Economical Route to Spirobenzo[ h ]chromanones

Author(s) -

Yang YanFang,

Shu XingZhong,

Luo JianYi,

Ali Shaukat,

Liang YongMin

Publication year - 2012

Publication title -

chemistry – a european journal

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.687

H-Index - 242

eISSN - 1521-3765

pISSN - 0947-6539

DOI - 10.1002/chem.201200126

Subject(s) - stereocenter , chemistry , cascade reaction , alkyl , catalysis , tandem , epoxy , cascade , medicinal chemistry , organic chemistry , materials science , enantioselective synthesis , composite material , chromatography

In tandem : A PtI 4 ‐catalyzed tandem reaction of epoxy alkynyl allyl ethers involving a cyclization, [1,2]‐alkyl migration, O→C allyl shift, aromatic cyclization sequence has been achieved to synthesize spirobenzo[ h ]chromanones. The reaction simultaneously forms two adjacent stereocenters, one of which is a quaternary carbon atom (see scheme).

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