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Emulsion Reactors: A New Technique for the Preparation of Molecular Imaging Probes
Author(s) -
Simms Ryan W.,
Kim Dong Hyun,
Weaver Darren M.,
Sundararajan Chitra,
Blacker Megan,
Stephenson Karin A.,
Valliant John F.
Publication year - 2012
Publication title -
chemistry – a european journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.687
H-Index - 242
eISSN - 1521-3765
pISSN - 0947-6539
DOI - 10.1002/chem.201200049
Subject(s) - biocompatible material , emulsion , computer science , microsphere , process engineering , chemistry , nanotechnology , materials science , chemical engineering , organic chemistry , biomedical engineering , engineering
Emulsions for labeling : A new strategy for the preparation of radiolabeled compounds with the use of emulsions was developed. This biocompatible platform demonstrated enhanced yields for labeling biovectors with 99m Tc, 18 F, and 68 Ga. Enhancements included reduction in the amount of starting material required, a decrease in the number of radiochemical impurities, and the ability to perform reactions at room temperature.