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Cover Picture: A Unified Strategy for the Asymmetric Total Syntheses of Diversonol and Lachnone C (Chem. Eur. J. 49/2011)
Author(s) -
Bröhmer Manuel C.,
Bourcet Emmanuel,
Nieger Martin,
Bräse Stefan
Publication year - 2011
Publication title -
chemistry – a european journal
Language(s) - English
Resource type - Reports
SCImago Journal Rank - 1.687
H-Index - 242
eISSN - 1521-3765
pISSN - 0947-6539
DOI - 10.1002/chem.201190250
Subject(s) - chromone , enantioselective synthesis , domino , aldol reaction , stereochemistry , lactone , chemistry , total synthesis , permission , philosophy , organic chemistry , catalysis , epistemology
A unified synthetic strategy for the asymmetric syntheses of the natural products diversonol and lachnone C (a class of chromone lactones isolated from the filamentous fungus Lachnum sp. BCC 2424) was developed by using the domino vinylogous aldol–oxa‐Michael reaction as the enantioselective key step. This general method allows the enantioselective access to these classes of natural products and should be applicable to other members of the tetrahydroxanthone and chromone lactone families. For more details see the Full Paper by S. Bräse et al. on page 13706 ff. We thank Anna Linsenmeier (KIT) for designing the figure and Ingo Wagner for giving permission to use the background photohgraph.