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Cover Picture: Rapid and Quantitative Disulfide Bond Formation for a Polypeptide Chain Using a Cyclic Selenoxide Reagent in an Aqueous Medium (Chem. Eur. J. 2/2011)
Author(s) -
Arai Kenta,
Dedachi Kenichi,
Iwaoka Michio
Publication year - 2011
Publication title -
chemistry – a european journal
Language(s) - English
Resource type - Reports
SCImago Journal Rank - 1.687
H-Index - 242
eISSN - 1521-3765
pISSN - 0947-6539
DOI - 10.1002/chem.201190000
Subject(s) - reagent , chemistry , aqueous solution , aqueous medium , disulfide bond , ab initio , computational chemistry , organic chemistry , biochemistry
An energetic diagram for the stochastic disulfide (SS) bond formation reaction of a polypeptide with a water‐soluble selenoxide reagent is depicted on the cover. In their Full Paper on page 481 ff. , M. Iwaoka et al. elucidate the reaction mechanism of this SS bond formation, through kinetic analysis and ab initio calculations.