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Accelerating the Multifunctionalization of Therapeutic Nanoparticles by Using a Multicomponent Reaction
Author(s) -
Zhou Hongyu,
Su Gaoxing,
Jiao Peifu,
Yan Bing
Publication year - 2012
Publication title -
chemistry – a european journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.687
H-Index - 242
eISSN - 1521-3765
pISSN - 0947-6539
DOI - 10.1002/chem.201103743
Subject(s) - computer science , nanomaterials , nanotechnology , nanoparticle , scheme (mathematics) , materials science , mathematics , mathematical analysis
Simpler and faster! Multifunctionalized nanoparticles are crucial for nanobiomedical applications, but their syntheses are tedious and time‐consuming. A multicomponent reaction on nanostructures is an excellent way to prepare such nanomaterials. The gold nanosystem illustrated in the scheme was built and shown to enhance cancer cell targeting and killing by combining the effects of a therapeutic drug with X‐ray radiation.