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Bismuth Triflate‐Catalyzed Asymmetric Allylation of Aromatic Aldehydes
Author(s) -
Li Zhiya,
Plancq Baptiste,
Ollevier Thierry
Publication year - 2012
Publication title -
chemistry – a european journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.687
H-Index - 242
eISSN - 1521-3765
pISSN - 0947-6539
DOI - 10.1002/chem.201103646
Subject(s) - enantioselective synthesis , bismuth , catalysis , trifluoromethanesulfonate , chemistry , organic chemistry , ligand (biochemistry) , combinatorial chemistry , biochemistry , receptor
Fits the BiL 2 : A highly enantioselective method for the catalytic allylation of aromatic aldehydes was developed using Bi(OTf) 3 and Trost's ( R , R )‐ProPhenol ligand (see scheme). Good yields and high enantioselectivities were obtained for a variety of aromatic aldehydes. The disclosed method is the first example of an enantioselective allylation reaction of aldehydes using a chiral Bi III complex. A preliminary characterization of the Bi III pre‐catalyst is also reported.
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