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Selected‐Control Fabrication of Multifunctional Fluorescent–Magnetic Core–Shell and Yolk–Shell Hybrid Nanostructures
Author(s) -
Liu Haiyan,
Wang Tingting,
Zhang Lingyu,
Li Lu,
Wang Y. Andrew,
Wang Chungang,
Su Zhongmin
Publication year - 2012
Publication title -
chemistry – a european journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.687
H-Index - 242
eISSN - 1521-3765
pISSN - 0947-6539
DOI - 10.1002/chem.201103066
Subject(s) - materials science , fabrication , shell (structure) , nanotechnology , superparamagnetism , fluorescence , nanostructure , nanocapsules , yttrium , nanoparticle , composite material , oxide , optics , magnetization , magnetic field , metallurgy , physics , alternative medicine , pathology , quantum mechanics , medicine
The selected‐control preparation of uniform core–shell and yolk–shell architectures, which combine the multiple functions of a superparamagnetic iron oxide (SPIO) core and europium‐doped yttrium oxide (Y 2 O 3 :Eu) shell in a single material with tunable fluorescence and magnetic properties, has been successfully achieved by controlling the heat‐treatment conditions. Furthermore, the shell thickness and interior cavity of SPIO@Y 2 O 3 :Eu core–shell and yolk–shell nanostructures can be precisely tuned. Importantly, as‐prepared SPIO@Y 2 O 3 :Eu yolk–shell nanocapsules (NCs) modified with amino groups as cancer‐cell fluorescence imaging agents are also demonstrated. To the best of our knowledge, this is the first report on the selected‐control fabrication of uniform SPIO@Y 2 O 3 :Eu core–shell nanoparticles and yolk–shell NCs. The combined magnetic manipulation and optical monitoring of magnetic–fluorescent SPIO@Y 2 O 3 :Eu yolk–shell NCs will open up many exciting opportunities in dual imaging for targeted delivery and thermal therapy.