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Copper(II)‐Catalyzed Monoarylation of Vicinal Diols with Diaryliodonium Salts
Author(s) -
Kuriyama Masami,
Hamaguchi Norihisa,
Onomura Osamu
Publication year - 2012
Publication title -
chemistry – a european journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.687
H-Index - 242
eISSN - 1521-3765
pISSN - 0947-6539
DOI - 10.1002/chem.201102770
Subject(s) - vicinal , chemoselectivity , diol , catalysis , copper , chemistry , combinatorial chemistry , organic chemistry
Selective and efficient : The copper(II)‐catalyzed selective monoarylation of vicinal diols with diaryliodonium triflates was successfully developed. In this catalytic process high chemoselectivity was achieved, even in the presence of a 1:1 mixture of the 1,2‐diol and the mono‐ol, and a wide range of substrates was tolerated, giving the monoarylated products in good to excellent yields (see scheme).