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Monoallylation of 1,2‐Diols by Pd/Sn Bimetallic Catalysis
Author(s) -
Kuriyama Masami,
Takeichi Tsubasa,
Ito Masaaki,
Yamasaki Noritsugu,
Yamamura Ryota,
Demizu Yosuke,
Onomura Osamu
Publication year - 2012
Publication title -
chemistry – a european journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.687
H-Index - 242
eISSN - 1521-3765
pISSN - 0947-6539
DOI - 10.1002/chem.201102709
Subject(s) - chemoselectivity , bimetallic strip , catalysis , substrate (aquarium) , diol , process (computing) , chemistry , computer science , organic chemistry , oceanography , operating system , geology
Efficient and mild : The selective monoallylation of 1,2‐diols was successfully developed with Pd/Sn bimetallic catalysis in good to excellent yields. This process was carried out with high substrate tolerance under mild conditions (see scheme). The catalyst system achieved the quite high chemoselectivity even in the presence of a 1:1 mixture of the 1,2‐diol and mono‐ol.