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Cu I /H 2 /NaOH‐Catalyzed Cross‐Coupling of Two Different Alcohols for Carbon–Carbon Bond Formation: “Borrowing Hydrogen”?
Author(s) -
Miura Takashi,
Kose Osamu,
Li Feng,
Kai Sun,
Saito Susumu
Publication year - 2011
Publication title -
chemistry – a european journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.687
H-Index - 242
eISSN - 1521-3765
pISSN - 0947-6539
DOI - 10.1002/chem.201101752
Subject(s) - carbon fibers , catalysis , hydrogen , coupling (piping) , carbon chain , chemistry , coupling reaction , reinforced carbon–carbon , medicinal chemistry , organic chemistry , materials science , composite number , composite material , metallurgy
Not borrowed : A new method was developed for the cross‐coupling of two different alcohols (see scheme). This carbon–carbon bond formation was realized by using a small amount of CuBr (0.05–0.2 mol %) and NaOH (4–20 mol %) in the presence of H 2 (1 atm), and provides an alternative procedure for longer‐chain alcohols. The catalytic cycle was different from those reported to date for the Guerbet reaction involving “borrowing hydrogen”.